The Science of Synthesis Editorial Board, together with the volume editors and authors, is constantly reviewing the whole field of synthetic organic chemistry as presented in Science of Synthesis and evaluating significant developments in synthetic methodology. Highlights of this volume of Knowledge Updates include chapters on the chemistry of platinum and iridium complexes, as well as the synthesis of triazoles, phthalazines, and quinazolines, heterosubstituted alkynes, nitrosoalkenes, and various haloalkane compounds.